Ozone Therapy
in New Hampshire
What is Ozone Therapy?
Ozone therapy delivers a precise mixture of medical-grade oxygen and ozone (O₃) into the body to support immune function, circulation, and healing. At Greenhouse Natural Medicine in Amherst, NH, a specialty-trained IV nurse administers ozone therapy in-office. Dr. Julia Greenspan, ND, trained with Dr. Frank Shallenberger and Dr. Robert Rowen and brought this therapy into the office over 5 years ago.
Ozone is a naturally occurring form of oxygen made of three oxygen atoms instead of two. Nikola Tesla patented one of the first ozone generators in 1896, and ozone has since been used to disinfect medical equipment, purify water, and treat infections and wounds.
What are the benefits of ozone therapy?
Research suggests ozone therapy helps reduce inflammation, support the immune system, improve circulation and oxygen delivery, and promote tissue healing. Laboratory studies show ozone has antiviral, antibacterial, and antifungal activity.
In small doses, ozone creates a mild, controlled stress response that prompts the body to increase its own antioxidant defenses, including glutathione, one of its most important antioxidants. Studies have explored ozone therapy for:
Chronic pain, including joint, back, and nerve pain
Chronic infections, including Lyme disease and other tick-borne illnesses
Wound healing and collagen production
Fatigue and low cellular energy
Supportive care in COVID-19 recovery
Ozone therapy is typically used alongside other treatments as part of an individualized plan, not as a replacement for conventional care. biolo
Ozone Therapy is known to have well-documented effects on reducing inflammation throughout the body, leading to anti-aging effects.
It can be used alone or with other treatment protocols to help the body regain balance. It is genuinely anti-aging and restorative medicine, strengthening the body’s ability to heal.
Is Ozone Therapy
Right for Me?
Medical Ozone has little to no serious side effects.
With conditions such as Tick-borne infections or mold biotoxin illness, symptom flares may occur after Ozone therapy, signaling that the body is detoxing the infection. These effects are common with any treatment for these types of chronic infections; they mean the body is reducing its pathogen or toxin load. Most patients feel very relaxed after treatment. This can be used as a stand-alone treatment or integrated with other therapies for recovery.
Frequently Asked Questions about Ozone Therapy
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Unfortunately, insurance doesn't cover ozone therapies. Patients wold need to confirm with their plan to know if HSA/FSA would cover therapies.
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This usually depends on the diagnosis and symptom severity. However, typical recommendations are 3-6 treatments for the best outcomes, spaced 1-2 weeks apart. For maintenance, you can do monthly or quarterly.
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Usually well tolerated during treatment. All patients are monitored during therapy by a licensed IV specialty nurse. Treatment usually takes 2 hours in the office.
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A good-sized meal with protein and healthy fats is required for a successful treatment. Hydrate, hydrate, hydrate!!!
Don't plan any major physical activity on the day of treatment to maximize effectiveness.
You can drive afterward, but if you want to bring a driver, that is also welcome.
Labs also need to be drawn beforehand with all patients receiving ozone therapy.
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MAH is a single-pass ozone therapy that involves extracting blood, infusing it with ozone, and returning it via IV. The patient is accessed in one arm, and blood is extracted and placed in an IV bag with ozone, saline, and heparin.
EBOO works much like dialysis, although it is not dialysis. The patient is accessed in each arm, and the machine moves blood through it and returns it to the patient after exposure to ozone and full-spectrum light. We can infuse more blood with ozone in less time.
Extracorporeal Blood Ozonation and Oxygenation
EBBO (Extracorporeal Blood Ozonation and Oxygenation) is an innovative therapy that enhances blood oxygen levels and promotes overall wellness. This treatment utilizes ozone and oxygen to improve circulation, detoxify the body, and stimulate the immune system, making this an appealing option for health-conscious individuals. EBOO can support recovery from acute and chronic illness, improve energy levels with chronic fatigue, and improve overall vitality. Greenhouse Natural Medicine continues to expand on advanced therapeutic options to support healing and recovery. This is also the perfect preventative therapy for athletic recovery and anti-aging support.
For more information, go to the EBOO page or call the office to book
How is ozone administered?
Ozone is delivered in-office through intravenous routes directly into the vein (MAH, EBOO), subcutaneous injection, trigger point injections, intramuscular injection, and into joints/tissues where there is pain/injury (this method is called Prolozone).
It can also be used in body cavities for inflammatory bowel disease conditions, chronic vaginal infections, and bagged ozone gas around chronic wounds on the body. In addition, Ozonated water can be consumed, and ozonated oil applied topically for wound healing.
Your journey starts here.
Let us help you determine if Ozone or Prolozone therapy is right for you.
Our clinic will also accept referrals from other medical practitioners who wish to add Ozone therapy to a patient’s treatment protocol. Please ask your practitioner to send us their medical order for Ozone therapy and a brief overview of the condition being treated.
This page was medically reviewed by Julia Greenspan, ND
Dr. Greenspan is a licensed naturopathic doctor at Greenhouse Natural Medicine in Amherst, NH, specializing in complex chronic illness, Lyme disease, mold biotoxin illness, and regenerative medicine. She earned her doctorate from NUNM in 2006 and is licensed by ILADS, AANP, and NHAND. She authored Rising Above Lyme Disease
Last reviewed: October 2026